Dr Alyssa Barry

Lab Head
Infection and Immunity Division
Walter and Eliza Hall Institute of Medical Research

+61 3 9345 2969
barry@wehi.edu.au

Research Activities

Millions of children are dying from malaria each year and more than one third of the world's population are at risk for infection with the most virulent malaria parasite, Plasmodium falciparum. A broadly effective malaria vaccine would be a major triumph for global public health yet years of research and clinical trials are yet to deliver such a vaccine. One of the major obstacles to this is the extraordinary genetic diversity and rapid evolution of the parasite. Our team utilises genomic, bioinformatic and population genetic tools to catalogue the range and distribution of this diversity, particularly in the Asia Pacific region. Our strong collaborative links to the Papua New Guinea (PNG) Institute of Medical Research is providing samples from malaria studies being conducted in the region. The research will help develop a framework upon which to plan and monitor malaria interventions and eventually elimination campaigns.

Current projects:
  • Mapping the geographic distribution of P. falciparum genomic diversity
  • Population genomics and molecular evolution of malaria vaccine antigens
  • Immunoepidemiology of the major variant surface antigen of P. Falciparum

Techniques/Expertise

Molecular biology
Genomics
Bioinformatics
Population genetics
Epidemiology/Immunoepidemiology

Collaborations

Ivo Mueller (PNGIMR)
Livingstone Tavul (PNGIMR)
Denise Doolan (QIMR)
Phil Felgner (UCI)
Karen Day (NYU)
James Beeson (WEHI)
Freya Fowkes (WEHI)
Caroline Buckee (Oxford/Santa Fe Institute)

Other members with similar research interests

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Dr Brad Sleebs

Chemical Biology The Walter and Eliza Hall Institute SEE FULL PROFILE >

A/Prof Michelle Dunstone

Department of Biochemistry and Molecular Biology Monash University SEE FULL PROFILE >

Prof Melanie Bahlo

Bioinformatics Division Walter and Eliza Hall Institute of Medical Research SEE FULL PROFILE >

Upcoming Events

  • Jun 23

    IgV Winter Seminar

    The Leveson
  • Jun 26

    Australian Society for Parasitology 2017 annual conference

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  • Jun 27

    EMBO-EMBL Symposium: New Approaches and Concepts in Microbiology

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