Prof Brendan Jenkins

Laboratory Head
Centre for Innate Immunity and Infectious Diseases
Hudson Institute of Medical Research

+61 3 9594 7218
brendan.jenkins@monash.edu

Research Activities

In vivo models assessing the mechanisms by which imbalanced STAT1 and STAT3 signalling from the IL-6 cytokine family common receptor gp130 contribute to inflammation, tumourigenesis, dysregulated lympho-hematopoiesis and bone metabolism

Techniques/Expertise

Gene targeting, mammalian cell culture techniques, immuno-detection techniques (eg immunohistochemistry, ELISA, Western blotting, flow cytometry), quantitative RT-PCR analyses

Collaborations

Simon Jones/Nicholas Topley (Cardiff, UK)
Andrew Robers (WEHI, Melbourne)
Matthias Ernst (Ludwig, Melbourne)
Robyn Starr (St Vincents Institute, Melbourne)
Matthew Gillespie and Jack Martin (St Vincents Institute, Melbourne)
Jane Armes (Mater Hospital, Brisbane)

Disease Models

Inflammation (peritonitis, endotoxic shock), gastric cancer, hematopoietic (spenomegaly, thrombocytosis) and lymphoid (lymphadenopathy) disorders , dysregulated bone metabolism.

Genetically Modified Organisms

gp130 knock-in mouse mutants crossed with STAT1/3, IL-6 and IL-11R KO mice

Other Lab Members

2 Research Assistants and 1 UROP student

Other members with similar research interests

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Dr Gabrielle Belz

Molecular Immunology Division Walter and Eliza Hall Institute of Medical Research SEE FULL PROFILE >

A/Prof Dena Lyras

Department of Microbiology Monash University SEE FULL PROFILE >

Dr Marina Harper

Department of Microbiology Monash University SEE FULL PROFILE >

Upcoming Events

  • Nov 27

    Australasian Society for Immunology 2017 Annual Scientific Meeting

    Brisbane Convention and Exhibition Centre REGISTER | MORE INFO
  • Nov 29

    Microbiome in Sexual, Maternal and Child Health Symposium

    AMREP Lecture Theatre REGISTER | MORE INFO
  • Dec 3

    MICROMON Molecular Biology Techniques 2017: An introductory course in recombinant DNA technology

    Monash University REGISTER | MORE INFO