Mr Dhanasekaran Sakthivel

PhD Student
Department of Biochemistry and Molecular Biology
Monash University

+61 4 1454 7007
dhansay@gmail.com

Research Activities

In my PhD program, I aim to examine the role of carbohydrate recognizing proteins of sheep (galectin 11 and 14 which have novel anti-parasitic activities in resistant animals) and how they interact with glycan’s present on the parasites surface in order to provide better insights in host immune resistance and for the design of a glycan based vaccine

Techniques/Expertise

  • Gene cloning, Protein expression in prokaryote and eukaryote system, Protein purification by various chromatographic approach, Macromolecular structure determination by X-ray crystallography. 
  • Gene expression analysis by quantitative reverse transcription PCR and western blot analysis.  Maintained animal virus (BTV, PPRV and pox) 
  • Handled animal parasites (H. contortus, Plasmodium berghei, Plasmodium yoleii, Plasmodium falciparum, plasmodium chabaudi and F. hepatica)

Disease Models

  • BALB/c mice for the propagation of Plasmodium berghei, Plasmodium yoleii, Plasmodium falciparum, plasmodium chabaudi
  • Chicken for the New castle disease virus vaccine
  • Sheep and goat for the propagation of  H. contortus immune response 
  • Bovine for the vaccine studies of Theileria annulata 

Genetically Modified Organisms

E. coli

Other members with similar research interests

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Dr Rob Center

Disease Elimination Program Burnet Institute SEE FULL PROFILE >

Dr Paul Gilson

Centre for Biomedical Research Burnet Institute SEE FULL PROFILE >

A/Prof Michelle Dunstone

Department of Biochemistry and Molecular Biology Monash University SEE FULL PROFILE >

Upcoming Events

  • Nov 27

    Australasian Society for Immunology 2017 Annual Scientific Meeting

    Brisbane Convention and Exhibition Centre REGISTER | MORE INFO
  • Nov 29

    Microbiome in Sexual, Maternal and Child Health Symposium

    AMREP Lecture Theatre REGISTER | MORE INFO
  • Dec 3

    MICROMON Molecular Biology Techniques 2017: An introductory course in recombinant DNA technology

    Monash University REGISTER | MORE INFO