Prof Elizabeth Hartland

VIIN Co-convenor
Department Head
Department of Microbiology and Immunology
University of Melbourne

+61 3 8344 8041
hartland@unimelb.edu.au

Research Activities

Research in our laboratory is focused on the identification of new virulence determinants in the bacterial pathogens, enteropathogenic and enterohemorrhagic E. coli (EPEC and EHEC) and Legionella. A major aim of this research is to investigate the interaction of novel virulence factors with host cell proteins and in particular to establish the biochemical and molecular basis of their role in pathogenesis. Our long term goal is to uncover new host processes and structures that are targeted by bacteria during infection leading to the design and development of novel anti-infective agents to treat a range of infectious diseases.

Techniques/Expertise

Genetic manipulation of bacterial pathogens
In vivo models of infection
Protein-protein interactions
Host-pathogen imaging
Innate immune signalling
Effector protein biochemistry

Collaborations

John Silke, WEHI
Andreas Strasser, WEHI
Gad Frankel, Imperial College London
Professor Ian van Driel, University of Melbourne
Professor Carmen Buchrieser, Institute Pasteur

Disease Models

Mouse model of Legionnaire's disease
Mouse model of diarrhoea 
Mouse model of inflammatory bowel disease

Research Images

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Upcoming Events

  • Jun 23

    IgV Winter Seminar

    The Leveson
  • Jun 26

    Australian Society for Parasitology 2017 annual conference

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  • Jun 27

    EMBO-EMBL Symposium: New Approaches and Concepts in Microbiology

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