Prof Elizabeth Hartland

Director
Hudson Institute of Medical Research

+61 3 8572 2700
elizabeth.hartland@hudson.org.au

Research Activities

Research in our laboratory is focused on the identification of new virulence determinants in the bacterial pathogens, enteropathogenic and enterohemorrhagic E. coli (EPEC and EHEC) and Legionella. A major aim of this research is to investigate the interaction of novel virulence factors with host cell proteins and in particular to establish the biochemical and molecular basis of their role in pathogenesis. Our long term goal is to uncover new host processes and structures that are targeted by bacteria during infection leading to the design and development of novel anti-infective agents to treat a range of infectious diseases.

Techniques/Expertise

Genetic manipulation of bacterial pathogens
In vivo models of infection
Protein-protein interactions
Host-pathogen imaging
Innate immune signalling
Effector protein biochemistry

Collaborations

John Silke, WEHI
Andreas Strasser, WEHI
Gad Frankel, Imperial College London
Professor Ian van Driel, University of Melbourne
Professor Carmen Buchrieser, Institute Pasteur

Disease Models

Mouse model of Legionnaire's disease
Mouse model of diarrhoea 
Mouse model of inflammatory bowel disease

Research Images

Other members with similar research interests

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Dr Odilia Wijburg

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Dr Shivani Pasricha

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Dr Hayley Newton

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Upcoming Events

  • Sep 25

    Global Virus Network Meeting 2017

    Doherty Institute, Melbourne, Australia MORE INFO
  • Oct 16

    LISSSD 2017

    Sofitel Fiji Resort and Spa MORE INFO
  • Oct 16

    VIIN Young Investigator Symposium 2017

    Walter and Eliza Hall Institute MORE INFO