< BACK TO FIND A MEMBER

Prof Brendan Jenkins

Laboratory Head
Centre for Innate Immunity and Infectious Diseases
Hudson Institute of Medical Research

brendan.jenkins@monash.edu

Research Activities

In vivo models assessing the mechanisms by which imbalanced STAT1 and STAT3 signalling from the IL-6 cytokine family common receptor gp130 contribute to inflammation, tumourigenesis, dysregulated lympho-hematopoiesis and bone metabolism

Techniques/Expertise

Gene targeting, mammalian cell culture techniques, immuno-detection techniques (eg immunohistochemistry, ELISA, Western blotting, flow cytometry), quantitative RT-PCR analyses

Collaborations

Simon Jones/Nicholas Topley (Cardiff, UK)
Andrew Robers (WEHI, Melbourne)
Matthias Ernst (Ludwig, Melbourne)
Robyn Starr (St Vincents Institute, Melbourne)
Matthew Gillespie and Jack Martin (St Vincents Institute, Melbourne)
Jane Armes (Mater Hospital, Brisbane)

Disease Models

Inflammation (peritonitis, endotoxic shock), gastric cancer, hematopoietic (spenomegaly, thrombocytosis) and lymphoid (lymphadenopathy) disorders , dysregulated bone metabolism.

Genetically Modified Organisms

gp130 knock-in mouse mutants crossed with STAT1/3, IL-6 and IL-11R KO mice

Other Lab Members

2 Research Assistants and 1 UROP student

Other members with similar research interests

prev next

Miss Michelle Clark

Infection and Immunity Division Walter and Eliza Hall Institute of Medical Research SEE FULL PROFILE >

Dr Erika Duan

La Trobe Institute for Molecular Science La Trobe University SEE FULL PROFILE >

Dr Holly Anderton

Inflammation Medicines Development SEE FULL PROFILE >

Upcoming Events

  • Feb 27

    Antimicrobials 2020

    Melbourne Exhibition and Convention Centre MORE INFO
  • Mar 6

    Australasian Bone and Joint Infection Conference

    MORE INFO
  • Mar 15

    2020 Antibody Biology and Engineering Gordon Research Conference

    Ventura Beach Marriott MORE INFO

Quick Links