Prof Brendan Jenkins

Laboratory Head
Centre for Innate Immunity and Infectious Diseases
Hudson Institute of Medical Research

+61 3 9594 7218
brendan.jenkins@monash.edu

Research Activities

In vivo models assessing the mechanisms by which imbalanced STAT1 and STAT3 signalling from the IL-6 cytokine family common receptor gp130 contribute to inflammation, tumourigenesis, dysregulated lympho-hematopoiesis and bone metabolism

Techniques/Expertise

Gene targeting, mammalian cell culture techniques, immuno-detection techniques (eg immunohistochemistry, ELISA, Western blotting, flow cytometry), quantitative RT-PCR analyses

Collaborations

Simon Jones/Nicholas Topley (Cardiff, UK)
Andrew Robers (WEHI, Melbourne)
Matthias Ernst (Ludwig, Melbourne)
Robyn Starr (St Vincents Institute, Melbourne)
Matthew Gillespie and Jack Martin (St Vincents Institute, Melbourne)
Jane Armes (Mater Hospital, Brisbane)

Disease Models

Inflammation (peritonitis, endotoxic shock), gastric cancer, hematopoietic (spenomegaly, thrombocytosis) and lymphoid (lymphadenopathy) disorders , dysregulated bone metabolism.

Genetically Modified Organisms

gp130 knock-in mouse mutants crossed with STAT1/3, IL-6 and IL-11R KO mice

Other Lab Members

2 Research Assistants and 1 UROP student

Other members with similar research interests

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Dr Nicole De Weerd

Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research SEE FULL PROFILE >

Prof Roger Nation

Monash Institute of Pharmaceutical Sciences Monash University SEE FULL PROFILE >

Prof Paul Hertzog

Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research SEE FULL PROFILE >

Upcoming Events

  • Apr 29

    International Day of Immunology

  • May 7

    VIIN Careers Evening 2018

    Woodward Conference Centre MORE INFO
  • May 10

    ASID Annual Scientific Meeting 2018

    Marriott Hotel Surfers Paradise MORE INFO