Prof Brendan Jenkins

Laboratory Head
Centre for Innate Immunity and Infectious Diseases
Hudson Institute of Medical Research

brendan.jenkins@monash.edu

Research Activities

In vivo models assessing the mechanisms by which imbalanced STAT1 and STAT3 signalling from the IL-6 cytokine family common receptor gp130 contribute to inflammation, tumourigenesis, dysregulated lympho-hematopoiesis and bone metabolism

Techniques/Expertise

Gene targeting, mammalian cell culture techniques, immuno-detection techniques (eg immunohistochemistry, ELISA, Western blotting, flow cytometry), quantitative RT-PCR analyses

Collaborations

Simon Jones/Nicholas Topley (Cardiff, UK)
Andrew Robers (WEHI, Melbourne)
Matthias Ernst (Ludwig, Melbourne)
Robyn Starr (St Vincents Institute, Melbourne)
Matthew Gillespie and Jack Martin (St Vincents Institute, Melbourne)
Jane Armes (Mater Hospital, Brisbane)

Disease Models

Inflammation (peritonitis, endotoxic shock), gastric cancer, hematopoietic (spenomegaly, thrombocytosis) and lymphoid (lymphadenopathy) disorders , dysregulated bone metabolism.

Genetically Modified Organisms

gp130 knock-in mouse mutants crossed with STAT1/3, IL-6 and IL-11R KO mice

Other Lab Members

2 Research Assistants and 1 UROP student

Other members with similar research interests

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Mr. Vishal Mistry

School of Applied Sciences RMIT University SEE FULL PROFILE >

Prof Philip Bardin

Monash Lung & Sleep department/Respiratory Research Monash Medical Centre SEE FULL PROFILE >

Mr Julio Carrera

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Upcoming Events

  • Aug 16

    12th Australasian Viral Hepatitis Conference

    The Sofitel Brisbane MORE INFO
  • Aug 23

    19th International Symposium on Staphylococci and Staphylococcal Infections

    Perth Convention and Exhibition Centre MORE INFO
  • Sep 11

    Zoonoses Conference

    MORE INFO