Prof David de Kretser
Sir John Monash Distinguished Professor
Centre for Reproductive Health
Hudson Institute of Medical Research
david.de.kretser@monash.edu
Licensing opportunities
Via a start up company, Parnata Biosciences, opportunities are present for commercial development of follistatin as an anti-inflammatory and anti-fibrotic agentic agent
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Research Activities
Role of the activins and follistatin in inflammation and tissue repair with specific foci on cystic fibrosis, acute respiratory distress syndrome and on reproductive tissue damage and the effects on male fertility and studies of their roles in transplant pathophysiologyTechniques/Expertise
Assays for the activins and follistatin in serum and tissues, clinical samples of a variety of diseases Immunocytochemistry, light and electron microscopyTransgenic models for the study of these proteins
Available recombinant follistatin
Collaborations
External:Robyn O'Hehir and the lung transplant unit at the Alfred Hospital
Karen Dwyer
Peter Cowan at St Vincents Centre for Immunology
Jane Girling
Peter Rogers at Univ of Melbourne
Prof Ville Pettila at the Univ of Helsinki
Brett Lidbury at ANU
Andreas Meinhardt at the Univ of Giessen, Germany
MIMR-PHI Institute:
A/Prof Mark Hedger
Carl Sprung
Craig Harrison
Peter Stanton
Jock Findlay
Disease Models
Via Univ of Giessen, models of inflammatory disease in the male reproductive tractDatabase of more than 2000 DNA samples from infertile men
