Prof Ross Coppel
Faculty of Medicine, Nursing and Health Sciences
Research ActivitiesStudies on mycobacteria and corynebacteria, including M. avium, M. smegmatis, C. glutamicum. Pathways of bacterial cell wall synthesis, host-pathogen biology including mycobacteria in macrophages, identification of genes involved in resisting phagocytosis. Mechanisms of phagocytosis.
Studies on various aspects of malaria biology. Focussing on asexual stages including proteins of the merozoite surface, the rhoptry and the molecular motor.
Vaccine studies including improved methods of delivery, DNA vaccination, oral immunization, transgenic plants, viral delivery. GMP production of recombinant proteins for human clinical trials.
Techniques/ExpertiseMolecular biology, protein expression, immunochemistry, immunofluorescence, protein-protein interactions, microarrays, bacterial genetics, TLC, cell wall analysis, sequencing, bioinformatics, Serology, ELISA, malaria gene knockout, malaria parasite culture, mouse models of malaria infection, malaria growth inhibition assays
CollaborationsMalcolm McConville, University of Melbourne
Christina Mitchell, Monash University
Mark von Itzstein Griffith University
Mohan Narla, New York Blood Centre
Eric Gershwin, UC Davis
Laurie Bannister, London
Prof Magdalena Plebanski
Prof Brian Cooke
CIs of the ARC Centre of Excellence in Structural and Functional Microbial Genetics
Disease ModelsMalaria in mice; Plasmodium chabaudi and Plasmodium yoelii
Genetically Modified Organisms4.1 KO mice
CD36 KO mice
Fcγ KO mice
Other Lab MembersPostdoctoral Scientists:
PhD and Honours students: