Research Activities
Proteins and other molecules on the cell surface of pathogens play a significant role in their colonisation and persistence. The aim of my work is to use whole cell phage-display to target these cell surface receptors/ molecules for the development of pathogen-specific antimicrobials, point-of-care diagnostics and vaccine candidates. The isolated peptides are usually pathogen-specific with unique modes of action and specificity, differentiating them from antibiotics used in human medicine.
Research Keywords
Researching in the following areas:
Phage display, Antimicrobial development, Diagnostics, Vaccine development
Techniques/Expertise
My interest is in the use of phage display and other combinatorial biochemistry techniques for the isolation of novel targets for the control of pathogens.