A/Prof Mark Hedger

NHMRC Senior Research Fellow
Centre for Reproductive Health
Hudson Institute of Medical Research

mark.hedger@monash.edu

Research Activities

Immunoregulation in the testis and male reproductive tract
Inflammatory networks in control of spermatogenesis and consequences for disease
Biology of macrophage populations in the testis and male reproductive tract

Regulation of inflammation, immunity and fibrosis by activin and follistatin

Techniques/Expertise

ELISA and RIA
Immunohistochemistry and flow cytometry
Histology and stereology
Cell separation and analysis
Small molecule purification and chromatography
Cell culture and in vitro biological assays

Quantitative RT-PCR

Collaborations

Prof Andreas Meinhardt (Institute for Anatomy and Cell Biology, Justus-Liebig University, Giessen)
Prof Kate Loveland (MIMR-PHI Institute of Medical Research)
Prof David de Kretser (MIMR-PHI Institute of Medical Research)
Dr Jane Girling (Dept of Obstetrics and Gynaecology, University of Melbourne, Royal Women's Hospital)
Dr Ashley Mansell (MIMR-PHI Institute of Medical Research)
Prof Robyn O'Hehir (Depts of Allergy, Immunology and Respiratory Medicine, Alfred Hospital, Monash University)
Dr Karen Dwyer (Immunology Research Centre, St. Vincent's Hospital, Melbourne)
A/Prof Tom Kotsimbos (Dept of Medicine, Monash University, Alfred Hospital)
Dr Greg Snell (Lung Transplant Service, Alfred Hospital)
Prof Peter Kerr (Dept of Nephrology, Monash Medical Centre)
Dr Paul Gregorevic (Baker IDI Heart and Diabetes Institute)
Dr Hans-Christian Schuppe (University Clinic for Urology, Pediatric Urology and Andrology, Justus-Liebig University)
Prof Martin Bergmann (Institute for Veterinary Anatomy, Histology and Embryology, Justus-Liebig University)
Dr Monika Fijak (Institute for Anatomy and Cell Biology, Justus-Liebig University)
Prof Ralph Middendorff (Institute for Anatomy and Cell Biology, Justus-Liebig University)
Prof Thomas Linn (University Clinic, Nutritional Medicine and Clinical Research Unit, Justus-Liebig University)

Disease Models

Reproductive failure due to systemic inflammation and infection
Chronic, non-infectious reproductive tract inflammation and pain
Idiopathic infertility
Cryptorchidism and reproductive tract dysgenesis

Genetically Modified Organisms

Activin and follistatin knock-out and transgenic mice

Other Lab Members

Rosemary Genovese
Sue Hayward
Julie Muir
Dr Mai Sarraj
Dr Julia Young
Adnan Sali
Rukmali Wijayarathna (PhD student)
Sivanjah Indumathy (PhD student)
Britta Klein (PhD student)
Constanze Maresch (PhD student)
Rashid Aldahhan (PhD student)
Nour Nicholas (PhD student)

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