Dr Nitin Patil

NHMRC Peter Doherty Fellow
Monash University


Research Activities

Throughout evolution, Nature has developed various mechanisms to produce, modify and transport biomolecules in specific cells. Inspired by these mechanisms, our research utilizes a multidisciplinary approach to develop new therapeutics. Our main goal is to develop oligonucleotides and peptide-based therapeutics. Considering the challenging chemistry associated with oligonucleotides and peptides that present different reactive functional groups, the newly developed chemistry needs to be selective, quantitative and bio-compatible, therefore our research also focuses on creating new chemistry tools for the selective modification of oligonucleotides and peptides, for efficient drug delivery into specific cells.
The key areas of interests:
1) Peptide Nucleic Acids (PNA) as antisense antibiotics
2) Backbone modified antisense oligonucleotides
3) Polymyxin based antibiotic drug development


  • Solid Phase Peptide Synthesis
  • Solid Phase Oligonucleotide Synthesis
  • Backbone modified oligonucleotides
  • Antimicrobial peptides
  • Antisense antibiotics
  • Organic synthesis of molecular probes and solid phase building blocks


Prof Jian Li
Tony Velkov

Upcoming Events

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    49th ASI Annual Scientific Meeting

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    World AIDS day

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    50th ASI Annual Scientific Meeting