A/Prof Kim Jacobson

Laboratory Head
Department of Biochemistry and Molecular Biology
Monash University

kim.jacobson@monash.edu

Research Activities

Progressive vaccine design and new therapeutics for B cell-derived cancers will rely on advances in our knowledge on the regulators that underpin B cell differentiation. Immune memory success relies on its adaptability: in response to different pathogens, variants of a single pathogen, and in balancing persistence with reactivation and terminal differentiation to plasma cells. This is likely achieved by producing a B cell memory population that is highly diverse.There are four different themes of our research into immunity formed after immunisation or viral infection. We study:
(i) Genetic networks underlying the plasticity and diversity of antibody responses
(ii) Epigenetic regulation of memory B cell formation and responses
(iii) Molecular regulation of cellular migration during immune responses
(iv) Formation of atypical and classical memory in chronic infectious diseases.

Disease Models

LCMV, Influenza

Other members with similar research interests

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Dr Odilia Wijburg

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Dr Amy Chung

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Dr Annette Fox

Research WHO Collaborating Centre for Reference and Research on Influenza SEE FULL PROFILE >

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