A/Prof Heidi Drummer
Program Director, Disease Eliination
"VIIN has allowed me to identify new collaborators and industry partners to conduct my research program. "
Licensing opportunitiesVaccine candidates for HCV
Contract research opportunitiesCapacity to produce recombinant proteins in mammallian systems. Stable cell line development for high level protein production.
VIETHEER, P. T., BOO, I., GU, J., MCCAFFREY, K., EDWARDS, S., OWCZAREK, C., HARDY, M. P., FABRI, L., CENTER, R. J., POUMBOURIOS, P. & DRUMMER, H. E. 2017. The core domain of hepatitis C virus glycoprotein E2 generates potent cross-neutralizing antibodies in guinea pigs. Hepatology, 65, 1117-1131.
MCCAFFREY, K., BOO, I., OWCZAREK, C. M., HARDY, M. P., PERUGINI, M. A., FABRI, L., SCOTNEY, P., POUMBOURIOS, P. & DRUMMER, H. E. 2017. An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry. J Virol, 91.
Research ActivitiesWe aim to develop novel vaccine candidates for Hepatitis C and HIV and seek to understand mechanisms of viral entry, immune evasion and natural immunity to Hepatitis C.
Techniques/ExpertiseMammalian, insect and bacterial protein expression systems, cell line development, monoclonal antibody production and characterization, single cell B cell isolation and IgG production, evaluation of immune responses to vaccine candidates, virus neutralization assays, protein purification and characterization, structural biology.
CollaborationsDr Fasseli Coulibaly
Dr Pantelis Poumbourios
Professor Ellie Barnes
A/Prof Joseph Torresi