Mrs Sheila Nankoberanyi

Clinical Research Coordinator
Baker IDI Heart and Diabetes Institute

s.nankoberanyi@nucleusnetwork.com.au

Research Activities

I have previously worked with P. Falciparum malaria in collaboration with a group from University of California San Francisco, specifically studying drug resistance & genetic factors underlying treatment outcomes in Uganda. To this end, I evaluated a high throughput genotypic technique for surveillance of SNPs mediating drug resistance; and characterized the distribution of markers & their clinical relevance. And we managed to publish three papers out of this work, which can be accessed online. To date I have expanded my interests to Onchocerciasis eradication through novel molecular and genomic tools. Here we aim to develop novel diagnostic tools for onchocerciasis & identify genetic markers for disease surveillance across different epidemiological zones. So far, I have developed a Loop mediated isothermal amplification (LAMP) assay for point of care applications with regards to onchocerciasis. Cumulatively, I have gained a lot of experience in molecular epidemiology specifically employing state of the art genomic tools to solve prominent infectious disease problems.

Techniques/Expertise

Molecular epidemiology, drug resistance, nematode genomics, assay development, next generation sequencing, translation research

Collaborations

University of California San Fransisco
WHO/TDR
Diagnostics For All

Disease Models

C. elegans for Alzheimer’s disease
Bush Rats for Onchocerciasis pathophysiology studies
Possums for parasite evolution studies

Other members with similar research interests

prev next

Mr Navin Karan

Victorian Infectious Diseases Reference Laboratory (VIDRL) - Melbourne Health The Peter Doherty Institute of Infection and Immunity SEE FULL PROFILE >

Dr Claudia Simm

Department of Biochemistry and Molecular Biology Monash University SEE FULL PROFILE >

Dr Laura Cook

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >