Dr Alyssa Barry

Lab Head
Infection and Immunity Division
Walter and Eliza Hall Institute of Medical Research

barry@wehi.edu.au

Research Activities

Millions of children are dying from malaria each year and more than one third of the world's population are at risk for infection with the most virulent malaria parasite, Plasmodium falciparum. A broadly effective malaria vaccine would be a major triumph for global public health yet years of research and clinical trials are yet to deliver such a vaccine. One of the major obstacles to this is the extraordinary genetic diversity and rapid evolution of the parasite. Our team utilises genomic, bioinformatic and population genetic tools to catalogue the range and distribution of this diversity, particularly in the Asia Pacific region. Our strong collaborative links to the Papua New Guinea (PNG) Institute of Medical Research is providing samples from malaria studies being conducted in the region. The research will help develop a framework upon which to plan and monitor malaria interventions and eventually elimination campaigns.

Current projects:
  • Mapping the geographic distribution of P. falciparum genomic diversity
  • Population genomics and molecular evolution of malaria vaccine antigens
  • Immunoepidemiology of the major variant surface antigen of P. Falciparum

Techniques/Expertise

Molecular biology
Genomics
Bioinformatics
Population genetics
Epidemiology/Immunoepidemiology

Collaborations

Ivo Mueller (PNGIMR)
Livingstone Tavul (PNGIMR)
Denise Doolan (QIMR)
Phil Felgner (UCI)
Karen Day (NYU)
James Beeson (WEHI)
Freya Fowkes (WEHI)
Caroline Buckee (Oxford/Santa Fe Institute)

Other members with similar research interests

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A/Prof Margaret Hellard

Centre for Population Health Burnet Institute SEE FULL PROFILE >

Dr Ashraful Haque

Immunology QIMR Berghofer Medical Research Ins SEE FULL PROFILE >

Ms Christelle Buffet

Department of Medicine (Royal Melbourne Hospital/Western Hospital) University of Melbourne SEE FULL PROFILE >

Upcoming Events

  • Aug 5

    Australasian Viral Hepatitis Elimination Conference 2019

    Novotel Sydney Brighton Beach, Brigton-Le-Sands MORE INFO
  • Aug 13

    International Veterinary Immunology Symposium (IVIS) 2019

    Renaissance Seattle Hotel 515 Madison Street, Seattle, Washington 98104, USA MORE INFO
  • Aug 26

    Student Open Day Hudson Institute of Medical Research

    Hudson Institute of Medical Research and Monash University MORE INFO