Dr Alyssa Barry

Lab Head
Infection and Immunity Division
Walter and Eliza Hall Institute of Medical Research

barry@wehi.edu.au

Research Activities

Millions of children are dying from malaria each year and more than one third of the world's population are at risk for infection with the most virulent malaria parasite, Plasmodium falciparum. A broadly effective malaria vaccine would be a major triumph for global public health yet years of research and clinical trials are yet to deliver such a vaccine. One of the major obstacles to this is the extraordinary genetic diversity and rapid evolution of the parasite. Our team utilises genomic, bioinformatic and population genetic tools to catalogue the range and distribution of this diversity, particularly in the Asia Pacific region. Our strong collaborative links to the Papua New Guinea (PNG) Institute of Medical Research is providing samples from malaria studies being conducted in the region. The research will help develop a framework upon which to plan and monitor malaria interventions and eventually elimination campaigns.

Current projects:
  • Mapping the geographic distribution of P. falciparum genomic diversity
  • Population genomics and molecular evolution of malaria vaccine antigens
  • Immunoepidemiology of the major variant surface antigen of P. Falciparum

Techniques/Expertise

Molecular biology
Genomics
Bioinformatics
Population genetics
Epidemiology/Immunoepidemiology

Collaborations

Ivo Mueller (PNGIMR)
Livingstone Tavul (PNGIMR)
Denise Doolan (QIMR)
Phil Felgner (UCI)
Karen Day (NYU)
James Beeson (WEHI)
Freya Fowkes (WEHI)
Caroline Buckee (Oxford/Santa Fe Institute)

Other members with similar research interests

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Dr Ashraful Haque

Department of Microbiology and Immunoloty University of Melbourne, Doherty Institute SEE FULL PROFILE >

Prof Bill Charman

Faculty of Pharmacy and Pharmaceutical Sciences Monash University SEE FULL PROFILE >

Dr Diana Hansen

Infection and Immunity Division Walter and Eliza Hall Institute of Medical Research SEE FULL PROFILE >

Upcoming Events

  • Aug 16

    12th Australasian Viral Hepatitis Conference

    The Sofitel Brisbane MORE INFO
  • Aug 23

    19th International Symposium on Staphylococci and Staphylococcal Infections

    Perth Convention and Exhibition Centre MORE INFO
  • Sep 11

    Zoonoses Conference

    MORE INFO