Prof Robert Pike

Director
La Trobe Institute for Molecular Science
La Trobe University

r.pike@latrobe.edu.au

Research Activities

Investigations into the specificity and role of complement proteases
The response of host cells to bacterial proteases
Specificity and role of bacterial proteases
Specificity and role and of active and inactive proteases of the scabies mite

Techniques/Expertise

Protein chemistry
Enzymology
Phage display mapping of enzyme specificity and binding specificity
Protein purification

Collaborations

Phil Bird, James Whisstock, Steve Bottomley (Monash Biochemistry)
Eleanor Mackie (Vet School, Univ. of Melbourne)
Prof. Jan Potempa (Jagiellonian University, Poland)
Prof Dave Kemp (QIMR)
Prof Paul Hertzog
A/Prof Neil O'Brien-Simpson
Prof Elizabeth Hartland

Disease Models

None in-house
Using model of periodontal disease with Neil O'Brien-Simpson
Using models of osteoclast differentiation and bone repair with Eleanor Mackie

Genetically Modified Organisms

PAR-1 and PAR-2 null mice

Other Lab Members

1 post-doctoral fellow
3 research assistants
5 PhD students

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