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Innate immunity,Viral immunology,Host-pathogen interactions,Protein trafficking,Viral pathogenesis
Molecular Mechanisms Viral Pathogenesis
Molecular
cell biology, molecular virology, and molecular immunology approaches,
including dynamic live cell imaging (e.g. quantitative confocal laser scanning
microscopy, fluorescence recovery after photobleaching [FRAP], bimolecular
fluorescence complementation), super-resolution light microscopy (including
direct stochastic optical reconstruction microscopy [dSTORM]), structural biology (including NMR and crystallography), in vivo
microtubule interaction assays (including quantitative imaging of the cytoskeleton),
functional genomics and proteomics (including next-generation sequencing,
RT-PCR, quantitative mass-spectroscopy), viral reverse genetics and infection, in
vivo viral infection/disease models, immune signalling assays, in vitro
protein trafficking/interaction assays, in vitro viral replication
assays.
Prof. Herve Bourhy# Institut Pasteur; Prof. Danielle Blondel# CNRS# France; Prof. Angus Lamond# University of Dundee,Profs. Makoto Sugiyama and Naoto Ito# Gifu University; Prof. Toyoyoki Ose# Hokkaido University,A/Prof. Peter Crack# University of Melbourne; Prof. Paul Gooley# Dr. Michael Griffin# Prof. Spencer Williams# University of Melbourne; Dr. Cameron Stewart# AAHL# Geeloing and Dr. Glen Marsh# AAHL# Geelong; Dr. Megan Dearnley and John Bingham# AAHL# Geelong; Dr. Toby Bell# Monash University
Rabies/lyssaviruses, Nipah/Hendra/paramyxoviruses, Ebola virus
PhD students: A. Brice# M. Aloi# T. Zhao# A. Harrison# E. Tudhope (as cosuperviser: A. Hossain# J. Zhan# R. Sharma# A. Rozario),Masters: Yilin Lynette Zhang# (as co-supervisor# Siqiong Zheng),Post docs: Stephen Rawlinson# Celine Deffrasnes ,RA: Cassandra David
IP relating to development of attenuated live vaccines for lyssaviruses including rabies virus. Potential IP development for antiviral drugs against lyssaviruses including rabies virus.
