Prof Stephen Kent

Laboratory Head
Department of Microbiology and Immunology
University of Melbourne

+61 3 8344 9939

Contract research opportunities

Immunity studies in HIV and Influenza. We have worked with major pharmaceutical groups to evaluate aspects of vaccine-induced immunity in both humans and non-human primates.

Research Activities

An HIV vaccine is urgently needed. The Kent lab is working towards this goal. Better vaccine strategies are needed to prevent HIV infection and disease. This requires an understanding of how HIV causes AIDS, including which immune responses control HIV replication and which contribute to disease. A better understanding of effective immunity will expand the pipeline to novel treatment and prevention strategies.

Current projects:
  • ADCC responses to HIV and Influenza
  • Immune escape from H/SIV
  • Env-specific T cells
  • Treg cells and H/SIV
  • Nanoparticle vaccines
  • NKT cells and H/SIV
  • Influenza-HIV vaccines


To further understand how immune responses can control HIV, we have developed multiple assays to measure immunity and the effect these immune responses have on the virus. We recently developed new techniques to measure antibody dependent cellular cytotoxicity (ADCC). We developed a very simple assay on small volumes of blood to measure ADCC responses and are now studying how useful it is in people with HIV and whether it forces the virus to mutate to escape this potentially important response. Although T cell immunity is effective against the virus, immune escape is a hallmark of effective T cell immunity.  


Drs David Cooper, Andrew Lloyd, Greg Dore, Anthony Kelleher, Sean Emery University of NSW
Dr Martyn French, University of Western Australia
Dr Damian Purcell, University of Melbourne
Dr Rob Center
Dr Miles Davenport, University of NSW
Dr Dale Godfrey, University of Melbourne
Dr Andrew Brooks, University of Melbourne
Dr Frank Caruso, University of Melbourne

Disease Models

Primate models of HIV/SIV and Influenza
Mouse models of HIV and OVA vaccination
Human clinical trials of HIV and Influenza immunity

Genetically Modified Organisms

MHC-defined primates

Other Lab Members

Dr Ivan Stratov (NHMRC Clinical Research Fellow)
Ms Sheilajen Alcantara (Technical Assistant)
Ms Thakshila Amarasena (Technical Assisant)
Ms Megan Schepers (Animal Technician)
Dr Matthew Parsons
Ms Sarah Lloyd, PhD student
Mr Hyon-Xhi Tan, PhD student
Mr Josh Glass, PhD student
Ms Fernanda Ana-Sosa Batiz, PhD student
Mr Wen Shi Lee, PhD student
Dr Amy Chung
Dr Adam Wheatley
Dr Jane Batten (Research support)
Mr Yi Liu, PhD student
Ms Anne Kristensen, Research Assistant
Ms Hillary Vanderven, PhD student
Ms Milla Mclean, Technical Assistant
Mr Matthew Worley, PhD Student
Mr Kevin Selva, PhD Student

Research Images

Other members with similar research interests

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Dr Gaoqian Feng

Centre for Biomedical Research Burnet Institute SEE FULL PROFILE >

Dr Jeff Butler

Australian Animal Health Laboratory CSIRO SEE FULL PROFILE >

Dr Louis Schofield

Infection and Immunity Division Walter and Eliza Hall Institute of Medical Research SEE FULL PROFILE >

Upcoming Events

  • Nov 27

    Australasian Society for Immunology 2017 Annual Scientific Meeting

    Brisbane Convention and Exhibition Centre REGISTER | MORE INFO
  • Nov 29

    Microbiome in Sexual, Maternal and Child Health Symposium

    AMREP Lecture Theatre REGISTER | MORE INFO
  • Dec 3

    MICROMON Molecular Biology Techniques 2017: An introductory course in recombinant DNA technology

    Monash University REGISTER | MORE INFO