Dr Greg Moseley
VIIN Executive Committee Member
Head, Viral Pathogenesis Lab
Department of Microbiology
Licensing opportunitiesIP relating to development of attenuated live vaccines for lyssaviruses including rabies virus. Potential IP development for antiviral drugs against lyssaviruses including rabies virus.
Research ActivitiesMolecular Mechanisms Viral Pathogenesis
Techniques/ExpertiseMolecular cell biology, molecular virology, and molecular immunology approaches, including dynamic live cell imaging (e.g. quantitative confocal laser scanning microscopy, fluorescence recovery after photobleaching [FRAP], bimolecular fluorescence complementation), super-resolution light microscopy (including direct stochastic optical reconstruction microscopy [dSTORM]), structural biology (including NMR and crystallography), in vivo microtubule interaction assays (including quantitative imaging of the cytoskeleton), functional genomics and proteomics (including next-generation sequencing, RT-PCR, quantitative mass-spectroscopy), viral reverse genetics and infection, in vivo viral infection/disease models, immune signalling assays, in vitro protein trafficking/interaction assays, in vitro viral replication assays.
CollaborationsProf. Herve Bourhy, Institut Pasteur; Prof. Danielle Blondel, CNRS, France; Prof. Angus Lamond, University of Dundee
Profs. Makoto Sugiyama and Naoto Ito, Gifu University; Prof. Toyoyoki Ose, Hokkaido University
A/Prof. Peter Crack, University of Melbourne; Prof. Paul Gooley, Dr. Michael Griffin, Prof. Spencer Williams, University of Melbourne; Dr. Cameron Stewart, AAHL, Geeloing and Dr. Glen Marsh, AAHL, Geelong; Dr. Megan Dearnley and John Bingham, AAHL, Geelong; Dr. Toby Bell, Monash University
Disease ModelsRabies/lyssaviruses, Nipah/Hendra/paramyxoviruses, Ebola virus
Other Lab MembersPhD students: A. Brice, M. Aloi, T. Zhao, A. Harrison, E. Tudhope (as cosuperviser: A. Hossain, J. Zhan, R. Sharma, A. Rozario)
Masters: Yilin Lynette Zhang, (as co-supervisor, Siqiong Zheng)
Post docs: Stephen Rawlinson, Celine Deffrasnes
RA: Cassandra David