Dr Greg Moseley

VIIN Executive Committee Member
Head, Viral Pathogenesis Lab
Department of Microbiology
Monash University

greg.moseley@monash.edu

Licensing opportunities

IP relating to development of attenuated live vaccines for lyssaviruses including rabies virus. Potential IP development for antiviral drugs against lyssaviruses including rabies virus.
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Research Activities

Molecular Mechanisms Viral Pathogenesis

Techniques/Expertise

Molecular cell biology, molecular virology, and molecular immunology approaches, including dynamic live cell imaging (e.g. quantitative confocal laser scanning microscopy, fluorescence recovery after photobleaching [FRAP], bimolecular fluorescence complementation), super-resolution light microscopy (including direct stochastic optical reconstruction microscopy [dSTORM]), structural biology (including NMR and crystallography), in vivo microtubule interaction assays (including quantitative imaging of the cytoskeleton), functional genomics and proteomics (including next-­generation sequencing, RT-PCR, quantitative mass-spectroscopy), viral reverse genetics and infection, in vivo viral infection/disease models, immune signalling assays, in vitro protein trafficking/interaction assays, in vitro viral replication assays.

Collaborations

Prof. Herve Bourhy, Institut Pasteur; Prof. Danielle Blondel, CNRS, France; Prof. Angus Lamond, University of Dundee
Profs. Makoto Sugiyama and Naoto Ito, Gifu University; Prof. Toyoyoki Ose, Hokkaido University
A/Prof. Peter Crack, University of Melbourne; Prof. Paul Gooley, Dr. Michael Griffin, Prof. Spencer Williams, University of Melbourne; Dr. Cameron Stewart, AAHL, Geeloing and Dr. Glen Marsh, AAHL, Geelong; Dr. Megan Dearnley and John Bingham, AAHL, Geelong; Dr. Toby Bell, Monash University

Disease Models

Rabies/lyssaviruses, Nipah/Hendra/paramyxoviruses, Ebola virus

Other Lab Members

PhD students: A. Brice, M. Aloi, T. Zhao, A. Harrison, E. Tudhope (as cosuperviser: A. Hossain, J. Zhan, R. Sharma, A. Rozario)
Masters: Yilin Lynette Zhang, (as co-supervisor, Siqiong Zheng)
Post docs: Stephen Rawlinson, Celine Deffrasnes
RA: Cassandra David

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