Dr Aaron Irving

Postdoctoral Fellow
Emerging Infectious Diseases
Duke-NUS Medical School

aaron.irving@duke-nus.edu.sg

Research Activities

Pattern recognition receptors and activation of innate immunity and inflammasome.
Viral infection and innate immunity.
Differences in innate immune activation and inflammasome sensing between bats and humans.

Techniques/Expertise

Mammalian cell culture (epithelial cells, bone marrow derived macrophages/dcs, macrophage lines, T cell lines, PBMCs, lung, liver, kidney, whole splenocytes)
Immuno-detection techniques (eg. ELISA, Western blotting, flow cytometry)
inflammasome activation
NGS and proteomics
TLR ligand screening
Gene knockdown (RNAi)
Confocal and live-cell microscopy
Molecular Biology (cloning, mutagenesis, library screening)
Viral infection assays (NBV, HeV, SeV, MuV, Zika, DV, SFV, Adv5, HSV1, EMCV, RSV, VZV)
Cellular movement (cellular migration, phagocytic uptake)

Disease Models

inflammasome
virus infections

Genetically Modified Organisms

mice
bat (KO cells)

Other Lab Members

Linfa wang

Other members with similar research interests

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Dr David Hoke

Department of Microbiology Monash University SEE FULL PROFILE >

Dr Anubhav Srivastava

Monash Institute of Pharmaceutical Sciences Monash University SEE FULL PROFILE >

Ms Julia Prier

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Upcoming Events

  • Aug 31

    The Inaugural Melbourne Immunotherapy Network Winter Retreat

    Vibe Hotel, Marysville MORE INFO
  • Sep 14

    ASID & ESCMID Perinatal Infectious Diseases Workshop 2018

    Q-Station MORE INFO
  • Oct 18

    VIIN Young Investigator Symposium 2018

    Walter and Eliza Hall Institute MORE INFO